Diagnosis of atrial fibrillation based on unsupervised domain adaptation

Mingyu Du1, Yuan Yang1, Lin Zhang1

  • 1Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Medicine and Engineering, No.37 Xueyuan Road, Haidian District, Beijing, China; Key Laboratory of Big Data-Based Precision Medicine, Ministry of Industry and Information Technology, No.37 Xueyuan Road, Haidian District, Beijing, China; School of Automation Science and Electrical Engineering, Beihang University, No.37 Xueyuan Road, Haidian District, Beijing, China.

PubMed

Insights

This study introduces a novel deep learning model for diagnosing atrial fibrillation using electrocardiograms (ECG). The model effectively trains on limited labeled and extensive unlabeled ECG data, achieving high diagnostic accuracy for this common elderly heart condition.

Area of Science:

  • Cardiology and Medical Informatics
  • Artificial Intelligence in Healthcare
  • Signal Processing

Background:

  • The global elderly population is increasing, leading to a rise in cardiovascular diseases.
  • Atrial fibrillation is a prevalent and life-threatening arrhythmia in older adults.
  • Accurate diagnosis of atrial fibrillation relies on electrocardiogram (ECG) signals, but large labeled datasets are scarce.

Purpose of the Study:

  • To develop a high-precision atrial fibrillation classification model using deep learning.
  • To address the challenge of limited labeled ECG data by leveraging unsupervised domain adaptation.
  • To improve the efficiency and accuracy of AI-driven ECG analysis for arrhythmia detection.

Main Methods:

  • A novel two-channel network model was designed to analyze ECG signals from multiple feature dimensions.
  • An innovative feature queue technique, incorporating a global centroid, was developed for stable and rapid network updates.
  • Unsupervised domain adaptation was employed, utilizing a small amount of labeled data with a large volume of unlabeled ECG data.
  • An improved domain discrepancy metric and a false label credibility evaluation formula were introduced to enhance learning from unlabeled data.

Main Results:

  • The two-channel network and feature queue technique enabled high-precision atrial fibrillation diagnosis with limited labeled data.
  • The model demonstrated strong generalization capabilities, achieving high performance metrics.
  • In the MIT-BIH Arrhythmia Database, the model reached 95.12% precision, 95.36% recall, 98.05% accuracy, and 95.23% F1 score.
  • In the MIT-BIH Atrial Fibrillation Database, performance was even higher, with 98.9% precision, 99.03% recall, 99.13% accuracy, and 99.08% F1 score.

Conclusions:

  • The proposed deep learning approach effectively diagnoses atrial fibrillation using ECG data.
  • The combination of a two-channel network and feature queue technique overcomes data limitations in ECG analysis.
  • This method offers a promising solution for accurate and efficient arrhythmia detection in clinical settings.

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