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Bilateral Cardiac Sympathetic Denervation as a Safe Therapeutic Option for Ventricular Arrhythmias

Soo Jung Park1, Deok Heon Lee1, Youngok Lee1

  • 1Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.

Journal of Chest Surgery
|August 14, 2023
PubMed

Insights

Bilateral cardiac sympathetic denervation (BCSD) is a safe and effective treatment for recurrent ventricular arrhythmias (VAs) unresponsive to other therapies. This study found BCSD offers short hospital stays and no major complications, with 70% of patients remaining symptom-free.

Area of Science:

  • Cardiology
  • Thoracic Surgery

Background:

  • Recurrent ventricular arrhythmias (VAs) pose a significant challenge despite conventional treatments like antiarrhythmic drugs, catheter ablation, and implantable cardioverter defibrillators.
  • Bilateral cardiac sympathetic denervation (BCSD) has emerged as a promising treatment for VAs, but its safety profile requires further investigation.

Purpose of the Study:

  • To evaluate the safety and efficacy of video-assisted bilateral cardiac sympathetic denervation (BCSD) in patients with refractory ventricular arrhythmias (VAs).

Main Methods:

  • A single-center study involving 10 patients with VAs underwent video-assisted BCSD.
  • The procedure was performed as a single-stage surgery for most patients, with a minority undergoing staged left and right denervation.
  • Outcomes assessed included postoperative complications, hospital stay duration, and pre- and post-operative VA symptoms.

Main Results:

  • The median hospital stay was brief, at 2 days, with a median surgical time of 113 minutes.
  • No significant intraoperative or postoperative complications were reported.
  • During a median follow-up of 13.5 months, 70% of patients experienced no VA-related symptoms.

Conclusions:

  • Video-assisted BCSD is a safe therapeutic option for patients with refractory VAs.
  • The procedure is associated with short hospitalizations and minimal complications.
  • BCSD provides a viable alternative for managing challenging VA cases.
Abstract

Keywords:
Cardiac arrhythmiasSympathectomyVideo-assisted thoracic surgery

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