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Post-COVID-19 Peripartum Cardiomyopathy: Experience from a Large Tertiary Referral Center
Shimrit Yaniv-Salem1, Lianne Dym1, Lior Nesher2
1Department of Gynecology and Obstetrics, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.
The Israel Medical Association Journal : IMAJ
|August 14, 2023
Summary
Pregnant individuals who recovered from mild COVID-19 may face increased risk of peripartum cardiomyopathy (PPCM). This study highlights the need for vigilance regarding PPCM in COVID-19 survivors during pregnancy.
Area of Science:
- Cardiology
- Obstetrics
- Infectious Diseases
Background:
- Peripartum cardiomyopathy (PPCM) is a rare pregnancy complication with unclear pathophysiology.
- Maternal and gestational factors are known PPCM risk factors.
- An increased incidence of PPCM was observed in COVID-19 survivors during the pandemic's initial wave.
Purpose of the Study:
- To report a case series of three patients diagnosed with PPCM following COVID-19 recovery during pregnancy.
- To investigate the potential link between COVID-19 and PPCM.
Main Methods:
- Single-center case study.
- Inclusion of all patients diagnosed with PPCM during the specified period.
- Review of electronic medical records.
Main Results:
- Three patients with prior asymptomatic or mild COVID-19 during pregnancy developed PPCM.
- Patients were tested for COVID-19 myocarditis, received medical treatment, and potentially wearable defibrillators.
- Follow-up assessments were conducted 1-9 months postpartum.
Conclusions:
- Mild COVID-19 may lead to endothelial damage, increasing PPCM risk in pregnant patients.
- PPCM should be considered a potential risk in COVID-19 survivors presenting with heart failure symptoms.
- Further research is required to validate this hypothesis and elucidate the pathophysiology.
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