Outcomes and survival of patients undergoing percutaneous vegetectomy for right heart endocarditis

Maria Riasat1, Balaram Krishna J Hanumanthu2, Arshan Khan3

  • 1Department of Internal Medicine, Mount Sinai Beth Israel, Manhattan, NY, United States.

Insights

The AngioVac system effectively removes vegetations in critically ill patients unsuitable for surgery, achieving a 93% survival rate. However, tricuspid regurgitation improvement was limited, necessitating further investigation.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Devices

Background:

  • AngioVac system facilitates percutaneous removal and debulking of vegetations.
  • It is indicated for patients who are not surgical candidates.
  • Right-sided infective endocarditis (RSIE) is a primary concern.

Purpose of the Study:

  • To identify demographics, echocardiographic features, indications, and survival outcomes of AngioVac vegetectomy.
  • To evaluate tricuspid regurgitation (TR) improvement post-procedure.
  • To assess the efficacy of AngioVac for RSIE.

Main Methods:

  • Systematic review of studies reporting AngioVac use for RSIE.
  • Primary outcome: survival on discharge.
  • Secondary outcomes: indications for AngioVac and TR improvement.

Main Results:

  • Intravenous drug abuse and cardiovascular implantable electronic devices were common risk factors (45% each).
  • Poor surgical candidacy (81%) was the main indication for AngioVac.
  • Survival at discharge was 93%, but TR improvement was only 16%.

Conclusions:

  • AngioVac is a viable alternative for critically ill patients unable to undergo surgery.
  • Further randomized controlled studies are needed to confirm survival and safety.
  • Tricuspid regurgitation changes require additional investigation.
Abstract

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