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Bibliometric and visual analysis of Kawasaki disease in children from 2012 to 2022

Zhengjiu Cui1,2, Fei Luo1,2, Jinjuan Wang2

  • 1First College of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.

Frontiers in Pediatrics
|August 14, 2023
PubMed

Insights

This bibliometric analysis reveals a growing body of research on Kawasaki disease (KD) in children, highlighting key trends and future research directions. The study identifies "immunoglobulin" as a central keyword and points to "KD pathogenesis" and "cardiovascular complications" as current hot topics.

Area of Science:

  • Pediatric Cardiology
  • Rheumatology
  • Bibliometrics

Background:

  • Kawasaki disease (KD) incidence is increasing in children, with significant cardiovascular implications.
  • Research on KD is extensive, yet bibliometric analyses using visualization methods are lacking.
  • This study addresses the need for a comprehensive bibliometric overview of KD literature.

Purpose of the Study:

  • To conduct a bibliometric analysis of publications on childhood Kawasaki disease from 2012 to 2022.
  • To identify publication output characteristics, research hotspots, and emerging frontiers.
  • To provide insights for future clinical and scientific research in pediatric KD.

Main Methods:

  • Screening literature from Web of Science, PubMed, and Scopus databases.
  • Utilizing Citespace, VOSviewer, and an online bibliometric platform for visual analysis.
  • Analyzing publications by country, institution, journal, author, keywords, and references.

Main Results:

  • A total of 4,867 publications were analyzed, showing a rising trend, especially since 2019.
  • China and KAOHSIUNG CHANG GUNG MEMORIAL HOSPITAL lead in publications; Ho-Chang Kuo is a highly impactful author.
  • "Immunoglobulin" is the most frequent keyword; Verdoni L, LANCET, 2020 had the highest burst intensity.

Conclusions:

  • Pediatric Kawasaki disease remains a significant global research focus.
  • An innovative "national-institutional-journal" model encourages international collaboration.
  • Current hot topics include KD pathogenesis, immunoglobulin resistance, and cardiovascular complications, with emerging frontiers in multisystem inflammatory syndrome and novel treatments.
Abstract

Keywords:
CiteSpaceVOSviewerbibliometric analysischildrenkawasaki diseasevisual analytics

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