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A Case of Ulcerative Colitis Induced by Paraneoplastic Syndrome?
Tao Zhang1, Zhu-Bin Pan1, Wen-Jia Tong2
1Department of General Surgery, Anhui Provincial Children's Hospital, Children's Hospital of Fudan University Anhui Hospital, Children's Hospital of Anhui Medical University, Hefei, 230000, People's Republic of China.
Insights
A rare paraneoplastic syndrome involving a yolk sac tumor and ulcerative colitis was observed in a child. Successful treatment led to complete symptom resolution and no recurrence after seven years.
Area of Science:
- Pediatric Oncology
- Gastroenterology
- Pathology
Background:
- Paraneoplastic syndromes typically manifest with endocrine, neurological, cutaneous, or hematologic issues.
- Digestive symptoms as the primary presentation of paraneoplastic syndromes are uncommon.
Background:
Paraneoplastic syndromes often cause endocrine, neurological, cutaneous, and hematologic pathologies, and cases with digestive symptoms as prominent cases are rare.
Case Description:
A 1-year-old child admitted to the emergency department with severe abdominal distension was later diagnosed with sacrococcygeal yolk cystoma with ulcerative colitis. After symptomatic management, surgical removal of the tumor, and JEB chemotherapy, the symptoms of ulcerative colitis disappeared completely. After 7 years of follow-up, the child grew and developed well, and there was no recurrence of tumor and ulcerative colitis.
Conclusion:
Yolk sac tumor with ulcerative colitis is a rare paraneoplastic syndrome with complex clinical manifestations.
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