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Isolation and Transcriptome Analysis of Plant Cell Types
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Deciphering plant cell-cell communications using single-cell omics data.

Jingjing Jin1, Shizhou Yu2, Peng Lu1

  • 1China Tobacco Gene Research Center, Zhengzhou Tobacco Research Institute of CNTC, Zhengzhou 450001, China.

Computational and Structural Biotechnology Journal
|August 14, 2023
PubMed
Summary
This summary is machine-generated.

Single-cell technologies enable detailed plant cell-cell communication (CCC) network construction. This review explores computational tools and methods for inferring plant CCC, highlighting current limitations and future research directions.

Keywords:
Cell-cell communicationOmicsPlantSingle-cell

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Area of Science:

  • Plant biology
  • Computational biology
  • Genomics

Background:

  • Plants possess diverse cell types that respond to environmental cues through intricate cell-cell communication (CCC).
  • Single-cell technologies offer unprecedented resolution for dissecting cellular heterogeneity and intercellular signaling pathways in plants.
  • Understanding plant CCC is crucial for comprehending their adaptive responses to environmental changes.

Purpose of the Study:

  • To review major computational models for inferring cell-cell communication networks in plants.
  • To summarize existing computational tools applicable to plant single-cell omics data for CCC analysis.
  • To identify limitations in current plant CCC research and propose future research avenues.

Main Methods:

  • Review of computational models for cell-cell communication inference.
  • Summary of computational tools utilizing single-cell omics datasets.
  • Analysis of existing literature on plant cell-cell communication.

Main Results:

  • Successful application of computational methods, primarily developed for animals, to infer plant CCC networks.
  • Identification of various computational tools and algorithms suitable for analyzing plant single-cell omics data.
  • Highlighting the potential of single-cell omics to build comprehensive plant CCC networks.

Conclusions:

  • Computational approaches are vital for deciphering plant cell-cell communication networks using single-cell data.
  • Further development and application of these tools are needed to overcome current limitations in plant CCC research.
  • Future research should focus on expanding the scope and accuracy of plant CCC inference for a deeper understanding of plant biology.