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Related Experiment Video

Updated: Jun 8, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Categorical Risk Stratification for Neonatal Early Onset Sepsis using Suspected Intraamniotic Infection and the

Anne-Marie Rick¹, Elizabeth Copp¹, Abigail Buckley¹

¹University of Pittsburgh.

Research Square

|August 14, 2023

Summary

A new categorical approach for early onset sepsis (EOS) using maternal criteria and newborn exams shows high sensitivity in identifying at-risk infants. This method is comparable to the existing EOS calculator for risk stratification.

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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

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Published on: August 12, 2020

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Last Updated: Jun 8, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

Area of Science:

Neonatal Medicine
Pediatric Infectious Diseases
Clinical Diagnostics

Background:

Early onset sepsis (EOS) is a critical neonatal condition requiring timely diagnosis.
Current diagnostic tools, like the EOS calculator, aid in risk stratification.
Maternal and newborn clinical signs are crucial indicators for potential infection.

Conclusions:

A categorical risk stratification using suspected IAI and newborn exams provides good discrimination for EOS.
This approach is comparable in performance to the EOS calculator.
Clinical criteria offer a valuable alternative or adjunct for EOS risk assessment.