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Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
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Diabetes mellitus impact on left ventricular assist device outcomes in heart failure patients: National Inpatient

Omar Obeidat1,2, Abdullah H Abdullahi1,2, Zeeshan Ismail1,2

  • 1University of Central Florida College of Medicine, Graduate Medical Education, Orlando, FL 32816, USA.

Future Cardiology
|August 14, 2023
PubMed

Insights

Diabetes mellitus (DM) increases heart failure (HF) risk, but DM patients receiving left ventricular assist device (LVAD) therapy showed similar in-hospital mortality, shorter stays, and lower costs compared to non-diabetic patients.

Area of Science:

  • Cardiology
  • Endocrinology
  • Medical Informatics

Background:

  • Diabetes mellitus (DM) is a significant risk factor for developing heart failure (HF).
  • Left ventricular assist device (LVAD) therapy is an option for advanced HF, but the impact of comorbidities like DM requires further investigation.

Purpose of the Study:

  • To evaluate the effect of diabetes mellitus on outcomes in patients undergoing left ventricular assist device implantation.
  • To assess in-hospital mortality as the primary outcome in diabetic versus non-diabetic LVAD patients.

Main Methods:

  • Retrospective cohort study design.
  • Analysis of the National Inpatient Sample administrative database.
  • Inclusion of 11,506 adult patients who received LVAD implantation.

Main Results:

  • 44.28% of LVAD patients had diabetes mellitus.
  • Diabetic patients experienced shorter hospital stays.
  • Diabetic patients had lower admission costs.
  • In-hospital mortality rates were similar between diabetic and non-diabetic LVAD patients after adjusting for covariates.

Conclusions:

  • Diabetes mellitus does not appear to significantly increase in-hospital mortality risk in LVAD patients.
  • LVAD therapy may offer comparable safety and efficiency in diabetic patients with refractory heart failure.
  • Findings contribute to understanding LVAD therapy risks and benefits in patients with comorbid DM.

Keywords:
LVADNISdiabetesfailureheart

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