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Updated: Aug 18, 2026

09:31
Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Published on: October 2, 2015
[Study of precancerous changes in the rat pleural mesothelium following exposure to asbestos using scanning electron
Abstract:
Rat pleural mesothelium was studied 16 to 22 months after intrapleural inoculation of chrysotile-asbestos. Irregular diffuse hyperplasia and focal solid and papillary pretumoral lesions were found. The morphological picture of these lesions in SEM and light microscopy have been discussed.

