Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Increased anxiety from fear of Omicron in China as compared to North America and Western Europe: a cross-sectional Kendall's tau-b analysis using the generalized anxiety disorder 7-item questionnaire.

Frontiers in psychiatry·2026
Same author

Single-Armed Longitudinal Intussusception Vasoepididymostomy in an Ex Vivo Rat Model With Video Demonstration.

Cureus·2026
Same author

Education and training in microsurgery: a current global overview.

Annals of medicine and surgery (2012)·2025
Same author

The Clinical Management of Professional Mixed Martial Arts Athletes Returning to Play after ACDF.

Current sports medicine reports·2025
Same author

Analyzing Procedural Time and Its Relationship to Performance in Microsurgical Training: A Pilot Study.

Cureus·2025
Same author

Trends in Sports-Related Upper Extremity Injuries Presenting to United States Emergency Departments: A Retrospective Analysis of National Injury Data.

Journal of clinical medicine·2025

Related Experiment Video

Updated: Jul 19, 2025

Microfluidic Model to Mimic Initial Event of Neovascularization
10:01

Microfluidic Model to Mimic Initial Event of Neovascularization

Published on: April 10, 2021

4.7K

Rat Microvascular Model is Tolerant to Technical Errors.

Joseph R Paladino1, YuanDian Zheng1, Konstantinos Gasteratos2

  • 1Department of Orthopedic Surgery, Columbia University Irving Medical Center, New York, New York.

Journal of Reconstructive Microsurgery
|August 14, 2023
PubMed
Summary
This summary is machine-generated.

The rat model tolerates many microsurgical errors, with only back-wall stitches significantly impacting arterial anastomoses. Venous anastomoses are more sensitive to specific technical errors like back-wall stitches, wide bites, and partial thickness bites.

More Related Videos

Author Spotlight: Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research
07:26

Author Spotlight: Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research

Published on: September 15, 2023

1.7K
Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

2.7K

Related Experiment Videos

Last Updated: Jul 19, 2025

Microfluidic Model to Mimic Initial Event of Neovascularization
10:01

Microfluidic Model to Mimic Initial Event of Neovascularization

Published on: April 10, 2021

4.7K
Author Spotlight: Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research
07:26

Author Spotlight: Creating Human Vascularized Micro-Tumors as Models for Translational Cancer Research

Published on: September 15, 2023

1.7K
Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

2.7K

Area of Science:

  • Microsurgery
  • Surgical technique analysis
  • Vascular anastomosis

Background:

  • Rat models are extensively used to study technical errors in vascular anastomoses.
  • Previous studies often involve experienced surgeons and examine isolated errors, potentially limiting generalizability.
  • Venous anastomoses have been underrepresented in prior research on technical error impact.

Purpose of the Study:

  • To comprehensively evaluate the impact of multiple technical errors on both arterial and venous anastomoses in a rat model.
  • To identify specific technical errors that significantly affect anastomosis patency.
  • To assess the resilience of the rat model to common microsurgical errors.

Main Methods:

  • Ninety-four arterial and 94 venous femoral anastomoses were performed on Sprague-Dawley rats by 47 microsurgeons.
  • Ten specific technical errors were systematically examined.
  • Statistical analysis was used to determine the causal relationship between errors and 30-minute postoperative patency.

Main Results:

  • Only the back-wall stitch demonstrated a significant causal effect on arterial anastomosis failure (p < 0.001).
  • For venous anastomoses, back-wall stitch, wide bite, and partial thickness bite significantly impacted patency (p < 0.001).
  • No other tested technical errors showed statistically significant effects on either arterial or venous anastomosis patency.

Conclusions:

  • The rat model exhibits high resilience to a variety of technical microsurgical errors.
  • Researchers should account for the rat model's resilience when designing and interpreting studies on surgical errors.
  • Microsurgery training should emphasize individual stitch quality over solely focusing on final anastomosis patency.