Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

17
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
17
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

155
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
155
Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

507
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
507
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

1.3K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.3K
Pneumonia IV: Management01:28

Pneumonia IV: Management

359
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
359

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Managing Fever Without Source in Well-appearing Young Infants: A Pragmatic Approach.

The Pediatric infectious disease journal·2026
Same author

Radar-Based Monitoring: A Proof of Principle Study in a Piglet Model for a Novel Approach in Non-Contact Vital Sign Monitoring.

Sensors (Basel, Switzerland)·2026
Same author

[Treatment of RSV in pediatric inpatients (Leave 5) and early effects of nirsevimab passive immunization in a regional German pediatric network].

Klinische Padiatrie·2026
Same author

[Outpatient parenteral antibiotic therapy in pediatric oncology patients with fever in neutropenia: literature review and scoping review].

Klinische Padiatrie·2026
Same author

Tuberculosis in a Large Day Care Center: A Case Report and Review of the Literature.

Klinische Padiatrie·2026
Same author

Suboptimal BMI in 5-year-old children born very preterm: a European multicountry cohort.

Archives of disease in childhood. Fetal and neonatal edition·2025

Related Experiment Video

Updated: Jul 19, 2025

Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

19.5K

[Update Perioperative Antibiotic Prophylaxis in Neonatology].

Arne Simon1, Clemens Magnus Meier2, Yeliz Baltaci1

  • 1Pädiatrische Onkologie und Hämatologie, Universitätsklinikum Homburg, Homburg, Germany.

Zeitschrift Fur Geburtshilfe Und Neonatologie
|August 14, 2023
PubMed
Summary

Perioperative antibiotic prophylaxis (PAP) for newborns requires careful consideration of antibiotic spectrum and duration. For vulnerable newborns, PAP should not exceed 24 hours to minimize risks.

More Related Videos

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

6.5K
Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

32.3K

Related Experiment Videos

Last Updated: Jul 19, 2025

Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

19.5K
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

6.5K
Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
05:32

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection

Published on: September 21, 2015

32.3K

Area of Science:

  • Neonatal Medicine
  • Pharmacology
  • Infectious Disease Prevention

Background:

  • Premature and term newborns represent a vulnerable patient population requiring specific considerations for perioperative antibiotic prophylaxis (PAP).
  • Understanding the nuances of PAP indications and dosing is crucial for optimizing outcomes in neonates.
  • The review addresses the critical balance between infection prevention and potential adverse effects of antibiotics in this demographic.

Approach:

  • This narrative review synthesizes current evidence and expert opinion on the principles of perioperative antibiotic prophylaxis in neonates.
  • It examines specific challenges related to the selection of antibiotics and appropriate dosing strategies.
  • The review emphasizes evidence-based guidelines for the duration of PAP in this sensitive patient group.

Key Points:

  • Perioperative antibiotic prophylaxis (PAP) in newborns necessitates a judicious approach to antibiotic selection, avoiding unnecessarily broad-spectrum agents.
  • Dosing of antibiotics in neonates must account for pharmacokinetic and pharmacodynamic differences.
  • Standard PAP duration should not exceed 24 hours, even in vulnerable newborns, to mitigate risks associated with prolonged antibiotic exposure.

Conclusions:

  • Optimizing perioperative antibiotic prophylaxis in newborns involves careful selection of agents and adherence to recommended durations.
  • Prolonged PAP beyond 24 hours in neonates is generally not indicated and may increase risks.
  • Evidence-based guidelines support a limited duration of PAP to ensure efficacy while minimizing potential harm in neonatal patients.