Platinum based theranostics nanoplatforms for antitumor applications

Area of Science:

• Nanomedicine
• Oncology
• Materials Science

Background:

• Platinum (Pt) nanoplatforms are biocompatible nanoagents with significant potential in cancer therapy.
• They offer selective, minimally invasive treatment modalities with integrated diagnostic and therapeutic capabilities.

Purpose of the Study:

• To review the research progress of platinum-based nanoplatforms in novel cancer therapeutic technologies.
• To highlight applications in chemotherapy, electrodynamic therapy, photodynamic therapy, photothermal therapy, and immunotherapy.

Main Methods:

• Review of existing literature on platinum-based nanoplatforms for cancer treatment.
• Discussion of representative examples across various therapeutic modalities.
• Brief overview of multimodal imaging techniques for diagnosis.

Main Results:

• Platinum nanoplatforms demonstrate efficacy in chemotherapy by damaging tumor cell DNA.
• They exhibit photothermal antitumor performance and radiotherapy sensitization properties.
• Potential for electrodynamic therapy, photodynamic therapy, and synergistic immunotherapy is highlighted.

Conclusions:

• Platinum nanoplatforms represent a promising frontier in multimodal cancer treatment strategies.
• Their versatility enables integrated diagnosis and therapy, improving treatment selectivity and minimizing damage.
• Further research into these nanoplatforms can lead to advanced cancer care solutions.