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Updated: Jul 19, 2025

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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
Published on: May 25, 2018
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Heritable genome editing: ethical aspects of a developing domain
1Department of Philosophy and Moral Sciences, Bioethics Institute Ghent, Ghent University, Ghent, Belgium.
Human Reproduction (Oxford, England)
|August 15, 2023
Summary
Human germline genome editing (GGE) raises complex ethical questions beyond safety, impacting future generations. Discussions must address parental preferences and societal views on normalcy and disability.
Area of Science:
- Reproductive biology and medicine
- Bioethics
- Genetics
Background:
- Scientific advancements in human germline genome editing (GGE) have intensified ethical debates.
- The discourse has shifted from categorical objections to pragmatic concerns like safety, efficacy, and potential misuse.
Conclusions:
- A comprehensive ethical framework for GGE must integrate pragmatic and fundamental moral questions.
- Future applications of GGE necessitate careful consideration of societal values and individual well-being.
- Ethical guidelines should respect individual traits and define boundaries for parental responsibilities in GGE.
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