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Updated: Jul 19, 2025

Depletion of Specific Cell Populations by Complement Depletion
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Role of complement in humoral immunity

Manuel Alfredo Podestà1, Nicholas Chun2

  • 1Renal Division, Department of Medicine, Transplantation Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Current Opinion in Organ Transplantation
|August 15, 2023
PubMed
Summary

Antibody-mediated rejection (AMR) after organ transplant is a major challenge. Complement inhibitors show promise in treating AMR by targeting the complement system, a key factor in rejection.

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