Obesity-hyperlipidemia, Hypertension, and Left Atrial Enlargement During Stroke in Young Adults

Shouye Zhang1, Peng Zuo

  • 1Department of Neurology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou, Jiangsu, People's Republic of China.

The Neurologist
|August 15, 2023
PubMed

Insights

Left atrial enlargement in young adults is not linked to stroke severity. However, obesity, hyperlipidemia, and hypertension are significant risk factors for left atrial enlargement in young stroke patients.

Area of Science:

  • Cardiology
  • Neurology
  • Public Health

Background:

  • Investigates the link between left atrial enlargement and stroke severity in young adults.
  • Examines clinical data differences between normal and enlarged left atrial groups.

Purpose of the Study:

  • To determine the association between left atrial size and stroke severity in young adults.
  • To identify clinical factors associated with left atrial enlargement in this demographic.

Main Methods:

  • Recruited 135 young stroke patients (Jan 2018-Dec 2021).
  • Classified patients into normal and enlarged left atrial groups based on size.
  • Analyzed the relationship between left atrial diameter and NIH Stroke Scale score, alongside clinical variables.

Main Results:

  • No significant correlation found between left atrial diameter and NIH Stroke Scale score (r=-0.045, P=0.603).
  • Hypertension, hyperlipidemia, elevated BMI, and obesity were associated with left atrial enlargement.
  • Logistic regression identified hyperlipidemia, hypertension, and obesity as significant predictors of left atrial enlargement in young stroke patients.

Conclusions:

  • Obesity, hyperlipidemia, and hypertension are significantly associated with left atrial enlargement in young adults experiencing stroke.
  • These factors are key indicators for left atrial enlargement in younger stroke populations.
Abstract

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