#AMRrounds: a systematic educational approach for navigating bench to bedside antimicrobial resistance

Area of Science:

• Infectious Diseases
• Clinical Microbiology
• Pharmacology

Background:

• Antimicrobial resistance (AMR) is a significant global health crisis.
• Clinicians face challenges in treating infections caused by resistant pathogens.
• Effective management requires integrating multiple scientific disciplines.

Purpose of the Study:

• To present a novel framework for systematically approaching clinical AMR.
• To encourage education and improve therapeutic decision-making in AMR-related illnesses.
• To provide clinicians with tools to navigate complex AMR cases.

Main Methods:

• Mobilizing laboratory testing for pathogen identification and susceptibility data.
• Understanding intrinsic pathogen resistance and epidemiological resistance trends.
• Recognizing acquired AMR mechanisms.
• Consolidating these factors for optimal pharmacological planning.

Main Results:

• The proposed framework aids in systematic clinical AMR management.
• Integration of diverse data improves therapeutic decision-making.
• Enhanced understanding of AMR mechanisms guides treatment strategies.

Conclusions:

• A systematic approach, grounded in education and multidisciplinary knowledge, is crucial for combating AMR.
• The presented framework empowers clinicians to optimize treatment for AMR infections.
• Improved clinical strategies are essential to address the growing threat of antimicrobial resistance.