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[Hemodynamic coupling of capillary, arterial and venous pressures in skeletal muscle vessels]
Abstract:
The dependence of capillary hydrostatic pressure (Pc) on changes of arterial (Pa) and venous (Pv) pressure was determined at different levels of the vascular tone in the m. gastrocnemius, the tone being either reduced with decentralization of the preparation or papaverine, or enhanced with noradrenaline. The Pc and Pv were closely related, the coefficients of the venous pressure transmission onto the capillary level being rather similar (93-97%) within a large range of Pv and vascular tone changes. The conjugation of Pc and Pa was disproportional as revealed in a decrease of the coefficient of arterial pressure transmission onto the capillary pressure, accompanying the Pa growth. This coefficient increased along with a reduction of the muscle arteries tone. The data obtained are regarded from the standpoint of participation of antero- and retrograde hemodynamic effects on capillary pressure and their role in forming the transcapillary fluid exchange in skeletal muscles.