[Lipid peroxidation by rat brain synaptosomes in sleep disorders]

Paradoxical sleep deprivation for 24 hrs reduced lipid peroxidation in synaptosomes from the rat brain cortex. Production of conjugated dienes was shown to decrease by 30% and fluorescent products--by 18%, the level of thiobarbituric acid reactive products being unchanged. The sleep disturbance resulted in a 25% activation of superoxide dismutase.