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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Newly Diagnosed SLE With APLS and Right Atrial Thrombus.

Ilya Ivyanskiy1, Shady Abdelbaki1, Muhammad Mohsin Qayyom1

  • 1Christiana Care Health System, Newark, Delaware, USA.

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Systemic lupus erythematosus (SLE) with antiphospholipid syndrome (APLS) can cause rare right atrial thrombi. Early anticoagulation and SLE management are crucial for this life-threatening condition.

Keywords:
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Area of Science:

  • Rheumatology
  • Cardiology
  • Hematology

Background:

  • Systemic lupus erythematosus (SLE) is a complex autoimmune disease affecting multiple organs.
  • Antiphospholipid syndrome (APLS) frequently co-occurs with SLE, characterized by arterial and venous thrombosis.
  • Intracardiac thrombi are rare but severe complications of APLS in SLE patients.

Observation:

  • This case report details a young patient newly diagnosed with SLE and APLS.
  • The patient presented with a rare complication: a thrombus in the right atrium of the heart.
  • Right atrial thrombus formation is an uncommon manifestation within the spectrum of cardiac involvement in APLS.

Findings:

  • The patient's condition involved both SLE and APLS, leading to the formation of a right atrial thrombus.
  • Treatment focused on anticoagulation, primarily with warfarin, alongside management of the underlying SLE.
  • This case highlights the potential for unusual thrombotic events in SLE-APLS.

Implications:

  • Increased clinical awareness of right atrial thrombi in SLE patients with APLS is warranted.
  • Prompt diagnosis and anticoagulation are vital to prevent potentially fatal outcomes.
  • This adds to the limited literature on this specific rare cardiac manifestation, emphasizing the need for vigilance.