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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Pushing forward in sarcoma with a new TCR targeting NY-ESO-1
Rusul Al-Marayaty1, Seth M Pollack1
1Northwestern University, Feinberg School of Medicine, Department of Medicine, Division of Oncology, Chicago, IL, USA.
Cell Reports. Medicine
|August 16, 2023
Abstract:
A phase 1 trial demonstrating the safety and efficacy of a novel NY-ESO-1-specific TCR-T cells by Pan et al.1 is a major step forward for adoptive T cell therapy in the clinical practice of advanced soft tissue sarcomas.
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