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Building a pathway to recovery: Targeting ECM remodeling in CNS injuries

Ayub Mohammed Butt1, Vimal Rupareliya1, A Hariharan1

  • 1Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Ahmedabad, Gandhinagar, Gujarat, India.

Brain Research
|August 16, 2023
PubMed
Summary

Extracellular matrix (ECM) remodeling is crucial for tissue repair but can cause scarring in central nervous system (CNS) injuries. Targeting ECM remodeling factors may promote axon regeneration and functional recovery after CNS trauma.

Keywords:
CNS injuriesECM remodelingFibrotic scarGlial scarNeuroregeneration

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