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To eat or not to eat: type 2 immunity controls food avoidance behavior
Albana L Kodra1, Daniel Mucida2
1Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.
None:
Growing evidence suggests that food allergies are regulated by neuroimmune interactions. However, the underlying molecular mechanisms remain unclear. Plum et al. and Florsheim et al. identify IgE-mediated mast cell activation, leukotrienes, and growth differentiating factor 15 (GDF15) as key regulators of the avoidance response to food allergens in mice.
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