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Updated: Jul 19, 2025

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
Published on: October 2, 2019
Sleep and memory consolidation in aging: A neuroimaging perspective
1Normandie Univ, UNICAEN, Inserm, U1237, PhIND "Physiopathology and Imaging of Neurological Disorders", Neuropresage Team, Institut Blood and Brain @ Caen-Normandie, Cyceron, Caen, France; UR2NF, Neuropsychology and Functional Neuroimaging Research Unit at CRCN, Center for Research in Cognition and Neurosciences and UNI, ULB Neuroscience Institute, Université libre de Bruxelles (ULB), Brussels, Belgium.
Abstract:
Recently acquired information is strengthened and consolidated during sleep. For hippocampus-dependent memory, this process is assumed to occur mainly during slow wave sleep. Changes in sleep patterns in older adults can contribute to the disruption of the consolidation process during sleep and thus lead to cognitive impairment. Current findings suggest that reduced gray matter volume, particularly in frontal areas, Aβ and tau accumulation in combination with age-related changes of specific oscillations during sleep may contribute to memory deficits. This non-exhaustive review aims at providing a comprehensive picture of the associations between sleep changes and memory consolidation in aging, mainly based on neuroimaging studies. Overall, data confirm the utmost importance of sleep for healthy aging and the need to develop interventions aiming at improving sleep to reduce cognitive decline observed with advancing age.
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