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Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
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Correlation between left atrial strain and left ventricular diastolic function in hypertensive patients

Jin Cai1, Zhongshu Liang2, Wenchang Feng3

  • 1Department of Cardiology, Third Xiangya Hospital, Central South University, Changsha 410013. 532143721@qq.com.

Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences
|August 16, 2023
PubMed

Insights

Left atrial strain changes occur early in hypertension, preceding structural changes. This strain, combined with echocardiographic indices, can help assess left ventricular diastolic function in hypertensive patients.

Area of Science:

  • Cardiology
  • Cardiovascular Imaging
  • Hypertension Research

Background:

  • Early detection of asymptomatic diastolic dysfunction is crucial for preventing heart failure in hypertensive patients.
  • Left atrial strain is suggested to aid in evaluating left ventricular diastolic function, but its role in hypertension requires further investigation.
  • This study explores left atrial strain using a two-dimensional speckle tracking technique in hypertensive individuals.

Purpose of the Study:

  • To evaluate changes in left atrial strain in hypertensive patients.
  • To investigate the relationship between left atrial strain and left ventricular diastolic function.
  • To identify early markers of diastolic dysfunction in hypertension.

Main Methods:

  • Eighty-two hypertensive patients and 59 healthy controls were enrolled.
  • Hypertensive patients were categorized into three groups based on diastolic function index count (0, 1, or ≥2).
  • Two-dimensional speckle tracking measured left atrial reservoir strain (LASr), conduit strain, and contraction strain.

Main Results:

  • Hypertensive patients showed lower LASr and conduit strain compared to controls.
  • LASr and conduit strain decreased with increasing diastolic dysfunction severity.
  • LASr positively correlated with measures of diastolic function (septal e´, lateral e´, E, E/A) and negatively with E/septal e´.

Conclusions:

  • Left atrial function changes precede structural alterations in early hypertension.
  • Left atrial strain, particularly when combined with indices like LASr/(E/septal e´), is a valuable tool for assessing left ventricular diastolic function in hypertensive patients.
Abstract

Keywords:
hypertensionleft atrial strainleft ventricular diastolic functionspeckle tracking imaging

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