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Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
Phthalic anhydride (PA): a valuable substrate in organic transformations
Kobra Nikoofar1, Mansoorehsadat Sadathosainy1
1Department of Organic Chemistry, Faculty of Chemistry, Alzahra University P.O. Box 1993891176 Tehran Iran k.nikoofar@alzahra.ac.ir kobranikoofar@yahoo.com +98 2188041344 +98 2188041344.
Abstract:
This review has been centralized on applications of phthalic anhydride (PA) as a valuable and significant heterocyclic substrate in two- and multicomponent organic reactions. The article has been subdivided into the following parts: (i) PA introduction by focusing on its characterization, synthesizing procedure, and multiple-aspect applications. In addition, the previous review articles based on PA have also been indicated; (ii) the applications of PA as a substrate have been subdivided into parts with a glance on the reaction components numbers; (iii) the applications of PA in esterification reactions; and (iv) some examples of PA in multistep synthesis. The review covers the corresponding literature up to the end of 2022. According to the abovementioned classifications, PA is a potent substrate to design a wide range of heterocyclic compounds that possess various kinds of properties and applications in chemistry, industry, and pharmaceuticals.
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