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Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
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Phthalic anhydride (PA): a valuable substrate in organic transformations
Kobra Nikoofar1, Mansoorehsadat Sadathosainy1
1Department of Organic Chemistry, Faculty of Chemistry, Alzahra University P.O. Box 1993891176 Tehran Iran k.nikoofar@alzahra.ac.ir kobranikoofar@yahoo.com +98 2188041344 +98 2188041344.
RSC Advances
|August 17, 2023
Summary
Phthalic anhydride (PA) is a versatile heterocyclic substrate for synthesizing diverse compounds. This review details PA
Area of Science:
- Organic Chemistry
- Heterocyclic Chemistry
Background:
- Phthalic anhydride (PA) is a key building block in organic synthesis.
- Its utility in various reactions, including esterification and multi-step synthesis, is well-established.
Purpose of the Study:
- To review the applications of phthalic anhydride (PA) as a substrate in organic reactions.
- To highlight PA's role in synthesizing heterocyclic compounds.
Main Methods:
- Literature review of PA applications up to 2022.
- Classification of PA's role based on reaction type and component number.
Main Results:
- PA is a potent substrate for designing a wide array of heterocyclic compounds.
- Applications span esterification, two-component, and multicomponent reactions.
- PA is crucial in multistep synthesis strategies.
Conclusions:
- Phthalic anhydride (PA) is indispensable for creating diverse heterocyclic structures.
- These compounds have significant applications in chemistry, industry, and pharmaceuticals.
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