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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
CLINICAL AND BEHAVIORAL PRACTICES OF PRIMARY HEALTHCARE PHYSICIANS IN ANTIBIOTICS PRESCRIBING IN GREECE
Aikaterini Toska1, Dimitra Latsou2, Maria Saridi1
1UNIVERSITY OF THESSALY, LARISSA, GREECE.
Most primary health physicians in Greece empirically prescribe antibiotics, often without diagnostic uncertainty. Findings inform strategies to improve antibiotic stewardship and prescription behavior in primary care.
Area of Science:
- Medical Science
- Public Health
- Epidemiology
Background:
- Antibiotic resistance is a growing global health threat.
- Appropriate antibiotic prescribing in primary care is crucial for combating resistance.
- Physician prescribing practices significantly influence antibiotic use.
Purpose of the Study:
- To assess clinical and behavioral antibiotic administration practices among primary health physicians.
- To identify factors influencing antibiotic prescribing in the Peloponnese Region, Greece.
Main Methods:
- A cross-sectional study utilizing questionnaires.
- Data collected from primary healthcare physicians in the Peloponnese Region.
- Study conducted between May and October 2020.
Main Results:
- A 75.8% response rate from 306 physicians.
- Most physicians empirically prescribe antibiotics for common conditions, except for respiratory infections.
- Over 66% reported no diagnostic uncertainty influencing prescription decisions.
- Nearly 40% noted increased antibiotic demand, though most were unaffected.
- Over 50% preferred prescribing branded antibiotics.
Conclusions:
- Physician prescribing practices vary and are influenced by multiple factors.
- Findings highlight the need for targeted interventions to optimize antibiotic use.
- Recommendations include implementing diagnostic tests, guidelines, and protocols to modify prescribing behavior.
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