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Updated: Jul 19, 2025

Author Spotlight: Expanding the Scope of Multiplex Immunoassays for Lyme Borreliosis Diagnostics and Pathogen Research
Published on: July 14, 2023
[Multiple erythema migrans, Borrelia lymphocytoma and neuroborreliosis in a child]
Kasper Schei1, Ellen H Modalsli2, Torbjørn Nag3
1Barne- og ungdomsavdelinga, Helse Møre og Romsdal, Ålesund sjukehus, og, Fakultet for medisin og helsevitskap, NTNU.
Background:
Lyme disease after a tick bite often presents as erythema migrans, yet less frequent variants of this disease, such as Borrelia lymphocytoma, multiple erythema migrans and neuroborreliosis, are also seen occasionally.
Case Presentation:
We report a case of a tick-bitten child who first presented with an indistinct macular erythema around the left eye and a more distinct macular erythema on and around the left ear. The next day, she developed a facial palsy.
Interpretation:
The case was interpreted as facial multiple erythema migrans and Borrelia lymphocytoma on the ear, followed by neuroborreliosis. The diagnosis of lymphocytoma was made from clinical findings and PCR of skin biopsy. She recovered quickly after intravenous ceftriaxone and is now healthy.

