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Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Lung infections in immunocompromised children
Alistair D Calder1, Giulia Perucca2, Sarah May Johnson3
1Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK. alistair.calder@gosh.nhs.uk.
Abstract:
Pulmonary infection is the leading cause of infectious morbidity and mortality in children with immune defects. We provide a comprehensive review of lung infections in immunocompromised children, with a focus on imaging findings and imaging-based management. We include an overview of the immune defences of the respiratory tract, the aetiologies of immune defects in children, the features of specific infections and important differential diagnoses and describe diagnostic strategies using imaging and non-imaging-based techniques.
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