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Magnitude and associated factors of mortality among patients admitted with COVID-19 in Addis Ababa, Ethiopia

Genanew Kassie Getahun1, Amare Dinku2, Dube Jara3

  • 1Menelik II Medical and Health Science College, Kotebe Metropolitan University, Addis Ababa, Ethiopia.

PLOS Global Public Health
|August 17, 2023
PubMed

Insights

COVID-19 mortality was high among hospitalized patients in Ethiopia. Older age, male gender, diabetes, hypertension, and chronic kidney disease significantly increased the risk of death from coronavirus disease.

Area of Science:

  • Public Health
  • Epidemiology
  • Infectious Diseases

Background:

  • The COVID-19 pandemic has caused significant global mortality and morbidity.
  • Comorbidities are associated with increased severity and mortality of COVID-19.
  • Infection fatality rates vary across studies, necessitating localized assessments.

Purpose of the Study:

  • To determine the mortality rate of COVID-19 patients admitted to Eka Kotebe General Hospital.
  • To identify factors associated with mortality among these hospitalized patients.

Main Methods:

  • An institutional-based cross-sectional study was conducted.
  • Data from 393 COVID-19 patient records (January-June 2021) were analyzed.
  • Bivariate and multivariable logistic regression identified determinant factors for mortality.

Main Results:

  • The COVID-19 mortality proportion was 8.1% (95% CI: 5.4-10.8%).
  • Factors independently associated with higher mortality included age >50 years, male gender, diabetes mellitus, hypertension, and chronic kidney disease.
  • Specific adjusted odds ratios (AOR) were: Age >50 [7.91], Male [2.09], Diabetes [2.64], Hypertension [2.67], CKD [12.04].

Conclusions:

  • COVID-19 mortality was notably high in the studied hospitalized population.
  • Age, male sex, diabetes, hypertension, and chronic kidney disease are independent predictors of COVID-19 mortality.
  • Targeted preventative strategies, including vaccination, are crucial for older adults and those with comorbidities.

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