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Updated: Jul 19, 2025

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
Recurrent Giant Cell Tumor of Bone with New Pulmonary Metastases 9 Years After En Bloc Distal Radius Resection: A
Matthew W DeFazio1, William Selove1, George Watts1
1Department of Pathology, UMass Memorial Medical Center, UMass Chan Medical School, Worcester, Massachusetts.
Case:
A 31-year-old man with a history of giant cell tumor of bone (GCTB) in the distal radius presents to clinic 9 years after en bloc distal radius resection. He was found to have a new soft tissue mass consistent with GCTB and new pulmonary metastases. Ultimately, he underwent excision of his soft tissue recurrence and partial lobectomy for his lung metastases.
Conclusion:
This case highlights the importance of having a high level of suspicion for local recurrence or metastasis, even years after wide resection and negative margins.
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