Angiomyolipoma with regional lymph node involvement and long-term follow-up study.

Area of Science:

• Nephrology
• Oncology
• Pathology

Background:

• Renal angiomyolipoma is a benign kidney tumor.
• The behavior of renal angiomyolipoma with regional lymph node involvement is not well understood.
• Distinguishing lymph node involvement as metastatic versus hamartomatous is clinically significant.

Observation:

• A single patient with renal angiomyolipoma exhibited regional lymph node involvement.
• The patient underwent long-term follow-up for 15 years.
• No evidence of tumor recurrence was observed during the follow-up period.

Findings:

• The absence of recurrence after 15 years supports a benign nature of lymph node involvement.
• Regional lymph node involvement in this case is interpreted as multicentric hamartomatous change.
• This finding challenges the assumption of metastasis from a malignant renal tumor.

Implications:

• This case suggests that renal angiomyolipoma with lymph node involvement may not require aggressive treatment for malignancy.
• Long-term surveillance may be sufficient for such cases.
• Further studies are warranted to confirm these findings in a larger cohort.