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Accessory Structures of the Skin: Hair Growth and Types01:20

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Hair growth begins with the production of keratinocytes by the basal cells of the hair bulb. As new cells are deposited at the hair bulb, the hair shaft is pushed through the follicle toward the surface. Keratinization is completed as the cells are pushed to the skin surface to form the shaft of hair that is externally visible. The external hair is completely dead and composed entirely of keratin. Hair can be cut or shaven without damaging the hair structure because the cut is superficial. Most...
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A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
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Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
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A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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Alopecia - New building blocks.

Lynne J Goldberg1

  • 1Department of Dermatology, Boston University Chobanian and Avedisian School of Medicine, Boston, Massachusetts; Boston Medical Center, Boston, Massachusetts.

Journal of the American Academy of Dermatology
|August 17, 2023
PubMed
Summary
This summary is machine-generated.

Accurate diagnosis and management of hair loss are challenging. This CME activity aims to improve dermatologists

Keywords:
Janus kinase inhibitorsalopecia areataandrogenetic alopeciabaricitinibcicatricial alopeciadiagnosishair lossnonscarring alopeciapatient counselingtreatment

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Area of Science:

  • Dermatology
  • Trichology

Background:

  • Alopecia presents a significant diagnostic and therapeutic challenge for healthcare providers.
  • Recent advancements necessitate a reevaluation of clinical skills for managing hair loss.

Purpose of the Study:

  • To educate dermatologists on identifying and differentiating various types of alopecia.
  • To provide guidance on managing diverse hair loss conditions.

Main Methods:

  • This continuing medical education (CME) activity focuses on practical diagnostic and management strategies.
  • Content is designed for succinct and simple delivery to clinicians.

Main Results:

  • The activity aims to improve dermatologists' ability to distinguish between different forms of hair loss.
  • It will equip clinicians with effective management approaches for various alopecias.

Conclusions:

  • Enhanced diagnostic and management skills are crucial for addressing the challenges of alopecia.
  • This educational initiative seeks to improve patient care for individuals experiencing hair loss.