Related Experiment Video
Updated: Jul 19, 2025

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
Published on: May 15, 2020
An Observational Study to Identify Drug-related Problems (DRP) in Routine Care and An Expert Panel Assessment to Rate
F V Wildhagen, M P Neininger, J Hensen
1Clinical Pharmacy, Institute of Pharmacy, Medical Faculty, and Drug Safety Center, Leipzig University and Leipzig University Hospital, Brüderstraße 32, 04103 Leipzig, Germany.
Drug-related problems (DRP) are common in peroral drug administration. Many DRPs pose high clinical risks but can be prevented by unit-dose dispensing systems (UDDS) with computerized physician order entry (CPOE) and clinical decision support systems (CDSS).
Area of Science:
- * Pharmaceutical Sciences
- * Patient Safety Research
- * Health Informatics
Background:
- * Drug-related problems (DRP) significantly compromise patient safety.
- * Unit-dose dispensing systems (UDDS) integrated with computerized physician order entry (CPOE) and clinical decision support systems (CDSS) show promise in mitigating DRPs.
- * Understanding the nature and preventability of DRPs in routine clinical settings is crucial for improving medication safety.
Purpose of the Study:
- * To identify and categorize DRPs in peroral drug administration.
- * To assess the clinical risk and preventability of identified DRPs by UDDS/CPOE/CDSS.
- * To provide evidence for the implementation of advanced dispensing systems to enhance patient safety.
Main Methods:
- * Observational study of routine peroral drug administration in surgical and internal medicine departments.
- * Categorization of 18 DRP categories by an expert panel based on clinical risk and preventability by UDDS/CPOE/CDSS.
- * Classification of DRPs into three levels based on the occurrence and patient reach of medication errors (ME).
Main Results:
- * A substantial number of DRPs were identified across 77 surgical and 149 internal medicine patients.
- * Four DRP categories were identified as high clinical risk: illegible medication names, un-prepared prescribed medication, incorrect medication preparation, and medication mix-ups for the wrong patient.
- * Twelve DRP categories were deemed highly preventable through the implementation of UDDS/CPOE/CDSS.
Conclusions:
- * Routine peroral drug administration is associated with a significant incidence of DRPs.
- * Many identified DRPs present high clinical relevance and are highly preventable with advanced technological interventions like UDDS/CPOE/CDSS.
- * Implementing UDDS/CPOE/CDSS can significantly enhance medication safety and reduce patient harm.
More Related Videos
12:20Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior
Published on: June 10, 2013
06:55Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Related Concept Videos
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Analysis of Population Pharmacokinetic Data
Drug Dosage Regimen: Overview
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Drug Abuse and Addiction: Pharmacological Phenomena