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Pharmacist Interventions for Adverse Drug Reactions in Palliative Care: A Multicentre Pilot Study
E Kose1, S Nakagawa2, K Niki3
1Department of Pharmacy; These authors contributed equally to this work.
Board-Certified Pharmacists in Palliative Pharmacy (BCPPP) interventions significantly improved patient daily living activities. BCPPP professionals managed more adverse drug reactions, enhancing palliative pharmacotherapy and symptom control.
Area of Science:
- Palliative Care Pharmacy
- Pharmacovigilance
- Clinical Pharmacy Practice
Background:
- Adverse drug reactions (ADRs) are a significant concern in palliative care, impacting patient quality of life.
- Optimizing pharmacotherapy management is crucial for effective symptom control in palliative settings.
- The role of specialized pharmacists in managing ADRs requires further investigation.
Purpose of the Study:
- To investigate ADRs in palliative care patients.
- To compare the effectiveness of interventions by Board-Certified Pharmacists in Palliative Pharmacy (BCPPP) versus non-BCPPP professionals.
- To assess the impact of pharmacist interventions on patient outcomes.
Main Methods:
- A multicenter prospective survey involving hospital and community pharmacists.
- Inclusion of patients experiencing new drug reactions during the study period.
- Evaluation of ADR severity and intervention impact using the integrated palliative care outcome scale.
Main Results:
- 79 ADR intervention reports from 69 patients were collected.
- Both BCPPP and non-BCPPP interventions significantly improved patients' activities of daily living (P < 0.001).
- BCPPP group demonstrated significantly more interventions for ADRs compared to the non-BCPPP group (P < 0.023).
Conclusions:
- BCPPP interventions are effective in improving symptom management in palliative care.
- Specialized palliative care pharmacists play a vital role in mitigating ADRs.
- Pharmacist expertise enhances patient outcomes and daily functioning in palliative settings.
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