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Arnold-Chiari Malformation Type I Evident After a Streptococcal Throat Infection in a Young Female: A Rare Case
Maryam Shahab1, Tamanna Nazir2, Sumaria Nazir2
1Internal Medicine, Central Park Physicians, New York, USA.
Abstract:
Arnold-Chiari malformation (ACM) is a rare neurological developmental disorder that presents at birth. No such cases have been reported in support of microbial infections causing Chiari malformation, yet there is evidence of how microorganisms can lead to brain abscess, brain empyema, and meningoencephalitis. We present a 23-year-old young woman with progressive back and leg pain after a streptococcal throat infection, followed by a single episode of syncope. Radiographs of the spine revealed a mild reversal of cervical spine curvature and minimal levocurvature of the lumbar spine. Magnetic resonance imaging of the brain showed herniation of the cerebral tonsils into the foramen magnum, which suggested the diagnosis of ACM type I. Neurosurgery was recommended for posterior fossa decompression, but the patient was reluctant to undergo the procedure. This is a rare case of ACM symptomology that became evident only after a streptococcal throat infection in a young adult female.
Insights
This study presents a rare case of Arnold-Chiari malformation (ACM) in a young woman whose symptoms emerged after a streptococcal infection. It highlights a potential, though unproven, link between infections and ACM symptom onset.
Area of Science:
- Neurology
- Developmental Biology
- Infectious Diseases
Background:
- Arnold-Chiari malformation (ACM) is a rare congenital neurological disorder.
- While microbial infections are known to cause various brain pathologies, a direct causal link to ACM has not been established.
- This case explores a potential association between streptococcal infection and the manifestation of ACM symptoms.
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