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Management of uremic pericarditis
Israel Journal of Medical Sciences
|June 1, 1986
Summary
This study shows that instilling triamcinolone hexacetonide and intermittent drainage effectively treats intractable pericardial effusion in uremic patients. The procedure provided immediate symptom relief with no complications and long-term success.
Area of Science:
- Nephrology
- Cardiology
- Interventional Procedures
Background:
- Uremic patients often develop pericardial effusion, which can lead to tamponade.
- Conservative treatments may fail for intractable pericardial effusion in hemodialysis patients.
Purpose of the Study:
- To evaluate the efficacy and safety of triamcinolone hexacetonide instillation with intermittent drainage for intractable pericardial effusion in uremic patients.
Main Methods:
- Subxiphoid pericardiotomy under local anesthesia for catheter insertion.
- Instillation of nonabsorbable steroid (triamcinolone hexacetonide) into the pericardial sac.
- Intermittent drainage via an indwelling catheter for 48-72 hours.
Main Results:
- All five patients achieved immediate symptom relief.
- No procedural complications were observed.
- No recurrent or constrictive pericarditis occurred during 3-8 years of follow-up.
Conclusions:
- Triamcinolone hexacetonide instillation combined with intermittent drainage is a safe and effective treatment for intractable uremic pericardial effusion.
- This minimally invasive approach offers long-term resolution of pericardial effusion without significant adverse events.