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Updated: Jul 19, 2025

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Cyclic Sulfinamides
Alexey V Dobrydnev1,2, Maria V Popova1,3, Yulian M Volovenko1
1Taras Shevchenko National University of Kyiv, Volodymyrska Street 60, Kyiv, 01033, Ukraine.
Abstract:
The literature on cyclic sulfinamides (put simply, sultims) published from 1989 to 2022 has been summarized and reviewed. The information is divided into two sections: the analysis of synthetic methods on the preparation of cyclic sulfinamides and the discussion of the chemical properties of cyclic sulfinamides focusing on their reactions and applications. The survey of the reaction conditions, provided in the most detailed way, and a critical view of the reaction mechanisms add an extra dimension to the text. The data presented will be useful to specialists in different areas, especially those who work in the field of synthetic organic and pharmaceutical chemistry.
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