Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

2.5K
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
2.5K
Pigmentation01:19

Pigmentation

2.5K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
2.5K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

3.9K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.9K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

2.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
Skin Cancer01:30

Skin Cancer

4.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
Reticular Dermis01:15

Reticular Dermis

2.6K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative 2-year drug survival of bimekizumab and brodalumab in second-line treatment of psoriasis.

Journal of the American Academy of Dermatology·2026
Same author

Ugeskrift for laeger·2026
Same author

Increasing the quantity of topical corticosteroids applied reduces the severity of psoriasis: results from two randomized controlled trials.

Clinical and experimental dermatology·2025
Same author

Ugeskrift for laeger·2025
Same author

Ugeskrift for laeger·2025
Same author

Ugeskrift for laeger·2025
Same journal

Dermatologie (Heidelberg, Germany)·2026
Same journal

[Medical care situation of people with vitiligo : A pilot and feasibility study on guideline-oriented management in German dermatology practices].

Dermatologie (Heidelberg, Germany)·2026
Same journal

[Erythroderma: etiology, diagnosis, and management-an overview].

Dermatologie (Heidelberg, Germany)·2026
Same journal

[New drug therapy approaches in the management of hidradenitis suppurativa].

Dermatologie (Heidelberg, Germany)·2026
Same journal

[Chronic hyperkeratotic plaques on the fingers and axillae in a mother and daughter].

Dermatologie (Heidelberg, Germany)·2026
Same journal

[63/m with a painful mass on the forehead following kidney transplantation : Preparation for the medical specialist examination: part 61].

Dermatologie (Heidelberg, Germany)·2026
See all related articles

Related Experiment Video

Updated: Jul 18, 2025

A Mouse Fetal Skin Model of Scarless Wound Repair
09:20

A Mouse Fetal Skin Model of Scarless Wound Repair

Published on: January 16, 2015

12.3K

[Scaling skin in infancy].

Georg Authried1, Christine Maria Weber2, Katharina Sillaber3

  • 1Landesklinikum Amstetten, Krankenhausstr. 21, 3300, Amstetten, Österreich. georg.authried@amstetten.lknoe.at.

Dermatologie (Heidelberg, Germany)
|August 18, 2023
PubMed
Summary
This summary is machine-generated.

A collodion baby presented with skin peeling and a membrane, but without infection or common genetic mutations. Mild cases may resolve with moisturizing care.

Keywords:
Collodion babyIchthyosisMolecular analysisNewbornsTopical treatment

More Related Videos

Author Spotlight: Insight into the Current Experimental Avian Skin Explant Methodologies
09:30

Author Spotlight: Insight into the Current Experimental Avian Skin Explant Methodologies

Published on: September 15, 2023

1.2K
Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics
14:14

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Published on: April 16, 2017

11.6K

Related Experiment Videos

Last Updated: Jul 18, 2025

A Mouse Fetal Skin Model of Scarless Wound Repair
09:20

A Mouse Fetal Skin Model of Scarless Wound Repair

Published on: January 16, 2015

12.3K
Author Spotlight: Insight into the Current Experimental Avian Skin Explant Methodologies
09:30

Author Spotlight: Insight into the Current Experimental Avian Skin Explant Methodologies

Published on: September 15, 2023

1.2K
Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics
14:14

Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics

Published on: April 16, 2017

11.6K

Area of Science:

  • Neonatal Medicine
  • Dermatology
  • Medical Genetics

Background:

  • Infantile skin conditions require accurate diagnosis.
  • Collodion membrane is a rare presentation in newborns.
  • Congenital ichthyoses encompass a group of genetic skin disorders.

Purpose of the Study:

  • To investigate the etiology of a neonate presenting with desquamation and a collodion membrane.
  • To differentiate the condition from infectious causes and known genetic subtypes of ichthyosis.

Main Methods:

  • Clinical examination of skin lesions including desquamation and collodion membrane.
  • Microbiological analysis of skin swabs.
  • Molecular genetic analysis for common congenital ichthyosis mutations.

Main Results:

  • No microbial growth was detected from skin swabs.
  • No common mutations associated with congenital ichthyoses were identified.
  • The infant presented with characteristics of self-healing collodion baby (SHCB).

Conclusions:

  • The infant's condition was consistent with self-healing collodion baby (SHCB), a subtype of ichthyosis.
  • Absence of infection and common genetic mutations supports a diagnosis of SHCB.
  • Mild presentations of SHCB may benefit from conservative management, including moisturizing creams.