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Analyzing Mitochondrial Morphology Through Simulation Supervised Learning
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Generative appearance replay for continual unsupervised domain adaptation.

Boqi Chen1, Kevin Thandiackal2, Pushpak Pati3

  • 1ETH AI Center, Zurich, Switzerland; Department of Computer Science, ETH Zurich, Switzerland.

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|August 19, 2023
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Summary

This study introduces Generative Appearance Replay for continual Domain Adaptation (GarDA), a novel method for unsupervised segmentation. GarDA adapts models to new data domains sequentially without needing past data, overcoming privacy and data limitations.

Keywords:
Cardiac segmentationContinual learningOptic disc segmentationProstate segmentationUnsupervised domain adaptation

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Area of Science:

  • Computer Science
  • Artificial Intelligence
  • Machine Learning

Background:

  • Deep learning excels with large labeled datasets, but real-world data presents challenges like incremental availability, domain shifts, and lack of labels.
  • Medical applications face strict privacy regulations prohibiting the retention of previously seen data.
  • Unsupervised domain adaptation (UDA) is crucial for leveraging unlabeled data across different domains.

Purpose of the Study:

  • To address challenges in unsupervised segmentation within continual learning scenarios involving domain shift.
  • To develop a method that adapts segmentation models sequentially to new domains using unlabeled data.
  • To enable adaptation without requiring access to previously seen data, enhancing practical applicability.

Main Methods:

  • Introduction of GarDA (Generative Appearance Replay for continual Domain Adaptation), a generative-replay based approach.
  • Sequential adaptation of a segmentation model to new domains with unlabeled data.
  • Leveraging and consolidating information from multiple domains through continual adaptation.

Main Results:

  • GarDA substantially outperforms existing techniques in unsupervised segmentation across multiple domains.
  • The method demonstrates effectiveness in continual learning scenarios with domain shift.
  • Successful evaluation on three datasets involving different organs and modalities.

Conclusions:

  • GarDA offers a practical solution for unsupervised segmentation in privacy-constrained, continual learning settings.
  • The generative-replay approach effectively handles domain shift without data retention.
  • This work advances the field of incremental UDA by removing the need for prior data access.