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Comparison of surgical strategies in patients with chronic subdural haematoma: a protocol for a network meta-analysis

Yujian Li1, Xiang Yang1, Huiqing Zhou2

  • 1Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

BMJ Open
|August 19, 2023
PubMed

Insights

This network meta-analysis will compare surgical and medical treatments for chronic subdural hematoma (CSDH). It aims to determine the most effective treatment strategy for CSDH patients, focusing on recurrence and functional outcomes.

Area of Science:

  • Neurosurgery
  • Evidence-Based Medicine
  • Medical Statistics

Background:

  • Chronic subdural hematoma (CSDH) is a common neurosurgical emergency, particularly in the elderly.
  • While surgery is the primary treatment, the optimal surgical strategy remains debated.
  • A comprehensive comparison of various treatments is needed.

Purpose of the Study:

  • To conduct a network meta-analysis comparing medical treatments and different surgical methods for CSDH.
  • To evaluate the efficacy of various interventions for CSDH.

Main Methods:

  • Systematic search of multiple databases (PubMed, Embase, etc.) up to April 2023.
  • Inclusion of randomized controlled trials and prospective non-randomized studies.
  • Network meta-analysis using STATA V.14 to compare recurrence rates and functional outcomes.

Main Results:

  • The analysis will rank interventions based on recurrence rates and functional outcomes.
  • Statistical methods will include inconsistency, subgroup, sensitivity, and publication bias assessments.

Conclusions:

  • The findings will provide evidence-based recommendations for CSDH treatment strategies.
  • This study aims to clarify the best surgical approach for managing chronic subdural hematoma.
Abstract

Keywords:
neurosurgeryprotocols & guidelinesstatistics & research methods

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