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[What to do when faced with a chronic elevation of transaminases]
A Delamarre1, G Boillet2, V de Lédinghen1
1Service d'hépatologie et de transplantation hépatique, hôpital Haut-Lévêque, centre hospitalier universitaire de Bordeaux, Bordeaux, France; BRIC, Inserm U1312, université de Bordeaux, Bordeaux, France.
Abstract:
Chronic elevation of transaminases is recurring issue in primary care. This article aims to be practical. It offers a quick reminder of epidemiology, pathophysiology, concept of normal values of transaminases, main causes (alcohol, fatty liver disease, viral hepatitis) and first-line assessment. Then, we will go further in less frequent causes, extra-hepatic causes and additional tests. We will precise what is the role of general practitioner in this care pathway and when to address patient to specialist.
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