Related Experiment Video
Updated: Jul 18, 2025

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
Pediatric Colonic Xanthomas, a Previously Unreported Colonoscopic Finding.
Jon A Vanderhoof1, Jeffrey D Goldsmith2, Rosemary Pauley3
1From the Department of Gastroenterology, Harvard Medical School, Boston Children's Hospital, Boys Town National Research Hospital, Boys Town, NE.
Gastrointestinal xanthomas, typically found in adults, were identified in the large intestine of a pediatric patient. These benign lesions in the sigmoid colon suggest they can be an incidental finding in children.
Area of Science:
- Gastroenterology
- Pediatric Pathology
- Gastrointestinal Oncology
Background:
- Gastrointestinal xanthomas are benign, polypoid lesions.
- They are typically found incidentally in the stomach of adults.
- Colonic xanthomas in children have not been previously reported.
Observation:
- A 15-year-old female patient presented with incidentally discovered sigmoid colon lesions.
- Histological examination confirmed the presence of xanthomas.
- This represents the first reported case of colonic xanthomas in a pediatric patient.
Findings:
- Colonic xanthomas can occur as an incidental finding in pediatric patients.
- These lesions possess distinct visual and histological characteristics.
- The presence of colonic xanthomas appears unrelated to symptoms or other illnesses.
Implications:
- Pediatric colonic xanthomas are likely benign and incidental.
- No specific follow-up is typically required for these lesions.
- This finding expands the known occurrence of xanthomas in the pediatric gastrointestinal tract.
More Related Videos
Related Concept Videos
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Endoscopic Procedures II: Colonoscopy
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

