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Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
Published on: May 10, 2024
Hypereosinophilic Syndrome with Pulmonary Involvement in Ulcerative Colitis
Anam Bashir1, Jose M Cabrera2, Mariko Suchi3
1From the Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Reactive eosinophilia is common in ulcerative colitis (UC). This case highlights the uncommon co-occurrence of hypereosinophilic syndrome (HES) and UC in a young patient, successfully treated with mepolizumab.
Area of Science:
- Gastroenterology
- Hematology
- Immunology
Background:
- Reactive eosinophilia is frequently observed in inflammatory bowel disease, particularly ulcerative colitis (UC).
- Hypereosinophilic syndrome (HES) coexisting with UC is a rare clinical presentation.
- Peripheral blood eosinophilia affects up to 30-40% of pediatric inflammatory bowel disease patients.
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