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Related Experiment Video

Updated: Jul 18, 2025

A Clinical Metaproteomics Workflow Implemented within Galaxy Bioinformatics Platform to Analyze Host-Microbiome Interactions Underlying Human Disease
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COVID-19 alters human microbiomes: a meta-analysis.

Rine Christopher Reuben1,2, Rémy Beugnon1,3,4, Stephanie D Jurburg1,5

  • 1German Centre of Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, Leipzig, Germany.

Frontiers in Cellular and Infection Microbiology
|August 21, 2023
PubMed
Summary

COVID-19 infection significantly alters the gut microbiome, reducing its diversity and causing shifts across populations. Respiratory microbiomes also change, with an increase in potentially pathogenic bacteria observed in infected individuals.

Keywords:
COVID-19SARS-C0V-2gut microbiomehost healthhuman microbiomeinfection

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Human Microbiome Research

Background:

  • Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes COVID-19, with ongoing discovery of its effects.
  • The human microbiome is crucial for health, and COVID-19 has been linked to microbiome alterations in specific populations.

Conclusions:

  • COVID-19 impacts the human-associated microbiome across populations, affecting both gut and respiratory sites.
  • Findings underscore the need for further research into the long-term consequences of COVID-19 on microbiota and host health.