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Published on: May 26, 2023
Emergency cesarean section in glanzmann thrombasthenia: Anaesthetic management without recombinant factor VIIa
Andal Priyanka1, Santhosh Arulprakasam1, Priya Rudingwa1
1Department of Anaesthesiology and Critical Care, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Abstract:
Glanzmann thrombasthenia (GT) is a congenital disorder inherited autosomal recessively, caused by deficiency of platelet membrane glycoprotein IIb-IIIa complex leading to defective platelet aggregation, and manifesting as mucocutaneous bleeding. Parturients with GT requiring emergency cesarean section are at high risk for perioperative bleeding complications. The anesthetist should be prepared with the necessary measures to control bleeding. This paper presents the successful management of a 23-year-old primigravida with GT undergoing cesarean section in a resource-limited setup where thromboelastography and recombinant factor VIIa (rFVIIa) are not available.
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