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Related Experiment Videos

Primary osteomyelitis caused by coagulase-negative staphylococci.

D Paley, C F Moseley, P Armstrong

    Journal of Pediatric Orthopedics
    |September 1, 1986
    PubMed
    Summary

    Coagulase-negative staphylococci (CONS) can cause subacute osteomyelitis in children. These bacteria, often dismissed as contaminants, require appropriate antibiotic treatment for resolution.

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    Area of Science:

    • Pediatric Infectious Diseases
    • Orthopedic Surgery
    • Microbiology

    Background:

    • Coagulase-negative staphylococci (CONS) are typically considered contaminants in bone infections.
    • Subacute osteomyelitis is a bone infection that develops gradually.

    Observation:

    • This report details two pediatric cases of subacute osteomyelitis of the distal tibia.
    • Pure cultures of CONS were isolated from bone in both patients.
    • Infection was multifocal in one patient and unifocal in the other, with CONS isolated from multiple samples.

    Findings:

    • CONS were the causative agents of osteomyelitis in these two children.
    • Symptoms persisted until targeted antibiotic therapy was administered.
    • Both patients showed clinical improvement following appropriate antibiotic treatment.

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    Implications:

    • CONS should not be automatically disregarded as mere contaminants in osteomyelitis cases.
    • Accurate identification and susceptibility testing of CONS are crucial for effective treatment.
    • Prompt and appropriate antibiotic therapy can lead to successful clinical resolution of CONS-induced osteomyelitis.