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Updated: Jun 25, 2026

Visualisation and Quantification of Intracellular Interactions of Neisseria meningitidis and Human α-actinin by Confocal Imaging
Published on: October 24, 2010
Vidjil add-on for MRD quantification of samples processed using the EuroClonality-NGS protocol
Guilherme Navarro Nilo Giusti1,2, Antonio Vítor Ribeiro3, Patrícia Yoshioka Jotta1
1Centro de Pesquisa Boldrini Centro Infantil Boldrini Campinas São Paulo Brazil.
Abstract:
Assessment of minimal residual disease in acute lymphoblastic leukemia by immune repertoire NGS requires spiking CDR3 sequences at known quantities into the patient's sample. Recently, the EuroClonality-NGS group released one of the most comprehensive protocols for this purpose. ARResT/Interrogate is a closed-source software for processing these NGS libraries, developed by this same group. Vidjil, an open-source alternative, currently cannot handle libraries prepared using this protocol. Here, we present a Vidjil add-on to solve this issue. EuroClonality-NGS prepared samples analyzed with Vidjil and ARResT/Interrogate were highly concordant (r = 0.998) and presented low error (root-mean-square error, RMSE = 0.112).
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