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Updated: Jul 18, 2025

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
A case report on letrozole-related maculopathy
Sitara Azeem1, Ahmed Al Hinai1, Nadiya Al Kharousi1
1Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Sultanate of Oman.
Letrozole, an aromatase inhibitor for breast cancer, can cause cystoid macular edema (CME), a rare but serious eye condition. Discontinuing letrozole may improve vision and reduce macular edema.
Area of Science:
- Ophthalmology
- Oncology
- Endocrinology
Background:
- Letrozole is a widely used aromatase inhibitor for hormone receptor-positive breast cancer in postmenopausal women.
- It functions by reducing estrogen synthesis, a key driver in many breast cancers.
- Ocular side effects associated with letrozole are uncommon but can significantly impact vision.
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